Gather the materials you need - a very soft cloth, such as a microfiber cloth, a specific leather solution or a soft unscented soap. How you do: Wet your cloth and gently rub the handbag until it's saturated, but not soaked. Once you are ready to use the cleaner, apply a small amount of the desired cleaning solution to the cloth Gently rub the stained area in a circular motion. Wipe off any residue and allow the area to dry for 30 minutes or longer. 

Not only is it important to keep the outside of your bag clean, but you need to maintain the inside as well. The lining of our  handbags is suede. 

The easiest way to clean this is to use an attachment on your vacuum cleaner. Small handle vacuums also work. Then repeat the steps like you did for the exterior. 

To keep the inside from becoming dirty, take a few preventative steps; for example, do not store pens without caps in your handbag. 

Make sure to cap all liquid items, such as lotions or hand sanitizers, before placing them in your bag. Keep all makeup in a separate bag to avoid any spills or stains.